PATHOLOGY

Detailed explanation-1: -Carrier testing is used to identify people who carry one copy of a gene mutation that, when present in two copies, causes a genetic disorder.

Detailed explanation-2: -Carrier screening determines whether or not an individual carries a change in one of their genes and if they are at increased risk of having a child affected with a genetic disease. Everyone carries abnormal genes, and in general, carriers have no symptoms or signs of the disease they carry.

Detailed explanation-3: -Recessive inheritance means both genes in a pair must be abnormal to cause disease. People with only one defective gene in the pair are called carriers. These people are most often not affected with the condition. However, they can pass the abnormal gene to their children.

Detailed explanation-4: -If a person has only one gene for a disorder, he or she is known as a carrier. Carriers often do not know that they have a gene for a disorder. They usually do not have symptoms or have only mild symptoms.

Detailed explanation-5: -Depending on the test, doctors can find if someone has an illness, is at risk for an illness, and/or is a carrier for an illness. A carrier doesn’t have the illness, but can pass the gene change to their children. Genetic testing usually can be done if the genetic changes for an illness are known.