PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cystic fibrosis affects the lungs, the pancreas, the digestive system, and other organs, resulting in symptoms ranging from breathing difficulties to recurrent infections. Which of the following terms best describes this?
A
incomplete dominance
B
epistasis
C
multiple alleles
D
pleiotropy
Explanation: 

Detailed explanation-1: -CF causes thick mucus that clogs certain organs, such as the lungs, pancreas, and intestines. This may cause malnutrition, poor growth, frequent respiratory infections, breathing problems, and chronic lung disease. There is no cure for CF.

Detailed explanation-2: -In the digestive system, CF mainly affects the pancreas. The pancreas is an organ that secretes substances that help with digestion and control the body’s levels of blood sugar. The abnormality in CFTR causes the secretions from the pancreas to become thick.

Detailed explanation-3: -CFTR controls the flow of water and certain salts in and out of the body’s cells. As the movement of salt and water in and out of cells is altered, mucus becomes thickened. In the reproductive system, the thickened secretions can cause obstructions and affect the development and function of the sexual organs.

Detailed explanation-4: -Cystic fibrosis (CF) is an inherited disease that causes thickened mucus to form in the lungs, pancreas and other organs. In the lungs, this mucus blocks the airways, creating lung damage and making it hard to breathe.

There is 1 question to complete.