PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The disorders are dominant
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The disorders are the result of codominance
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The disorders are the result of incomplete dominance
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The disorders are sex-linked
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Detailed explanation-1: -Since it’s passed down on the X chromosome, red-green color blindness is more common in men. This is because: Males have only 1 X chromosome, from their mother.
Detailed explanation-2: -As hemophilia is an X-linked disease, it is more common in males as they have only one X-chromosome, and a defect in one copy of the gene is sufficient to cause the disease.
Detailed explanation-3: -Color blindness is more common in men than in women because the genes responsible for color blindness are located on the X chromosomes. Such a defect is due to recessive genes, which occur on the ‘X’ chromosome.
Detailed explanation-4: -Males have only one X chromosome (XY). The recessive allele on the X chromosome of males is not masked. If a male inherits a recessive allele, he suffers from the disease.
Detailed explanation-5: -Males are more likely to be affected than females. Human color vision is normally trichromatic that is the mixture of red, green and blue lights. Red-green color blindness is the most common type. It affects 8% male and 0.5% female worldwide.