PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In Somatic Cell Gene Therapy, the genes transferred are usually normal alleles that could “ ____ “ the mutant or disease alleles of the recipient
A
treat
B
correct
C
incorrect
D
heal
Explanation: 

Detailed explanation-1: -Abstract. Somatic gene therapy involves the introduction of novel genetic material into somatic cells to express therapeutic gene products. This emerging technology holds great promise for the treatment of both inherited and acquired diseases.

Detailed explanation-2: -1) Somatic gene therapy entails the transfer of a gene or genes into body cells other than germ (egg or sperm) cells with effect only on the patient. The new genetic material cannot be passed on to offspring. Examples of Somatic gene therapy have already proven to be clinically effective.

Detailed explanation-3: -Somatic cell gene therapy is accepted to treat many disorders such as muscular dystrophy, cancer, cystic fibrosis, certain infectious diseases, etc. A single gene disorder like haemophilia, thalassaemia, cystic fibrosis, etc. have good chances of being cured by somatic cell gene therapy.

Detailed explanation-4: -Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Gene therapies can work by several mechanisms: Replacing a disease-causing gene with a healthy copy of the gene. Inactivating a disease-causing gene that is not functioning properly.

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