PATHOLOGY

Detailed explanation-1: -Some genetic disorders are caused by recessive alleles of a single gene on an autosome. An example of autosomal recessive genetic disorders are Tay-Sachs disease and cystic fibrosis. Children with cystic fibrosis have excessively thick mucus in their lungs, which makes it difficult for them to breathe.

Detailed explanation-2: -Most genetic disorders that result in sterility or childhood death are caused by recessive mutations, DNA sequence variants that are harmless when a person carries only one copy.

Detailed explanation-3: -These disorders are most often single gene defects. They follow the same pattern of inheritance as other single gene disorders. Most are autosomal recessive.