PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Homozygous
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Heterozygous
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Allele
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Chromosome
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Detailed explanation-1: -"Allele” is the word that we use to describe the alternative form or versions of a gene. People inherit one allele for each autosomal gene from each parent, and we tend to lump the alleles into categories. Typically, we call them either normal or wild-type alleles, or abnormal, or mutant alleles.
Detailed explanation-2: -Each variation of a gene is called an allele (pronounced ‘AL-eel’). These two copies of the gene contained in your chromosomes influence the way your cells work. The two alleles in a gene pair are inherited, one from each parent.
Detailed explanation-3: -Explained in greater detail, each gene resides at a specific locus (location on a chromosome) in two copies, one copy of the gene inherited from each parent. The copies, however, are not necessarily the same. When the copies of a gene differ from each other, they are known as alleles.
Detailed explanation-4: -allele, also called allelomorph, any one of two or more genes that may occur alternatively at a given site (locus) on a chromosome. Alleles may occur in pairs, or there may be multiple alleles affecting the expression (phenotype) of a particular trait.
Detailed explanation-5: -A gene is a stretch of DNA or RNA that determines a certain trait. Genes mutate and can take two or more alternative forms; an allele is one of these forms of a gene. For example, the gene for eye color has several variations (alleles) such as an allele for blue eye color or an allele for brown eyes.