PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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1 in 4
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1 in 2
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1 in 3
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3 in 5
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Detailed explanation-1: -If both parents carry a defective cystic fibrosis gene, each pregnancy has a 25 percent chance of producing a child with cystic fibrosis. The cystic fibrosis gene is most common in Caucasians of northern European descent.
Detailed explanation-2: -The parents only have dominant, non-CF genes to pass on and thus 100% of the offspring will have non-CF genes. ff Ff f F Ff Each carrier has a 50/50 chance of passing their CF gene onto their offspring which results in ΒΌ chance that one child will get both CF genes.
Detailed explanation-3: -If you are born to parents who both carry the same autosomal recessive gene, you have a 25% (1 in 4) chance of inheriting the abnormal gene from both parents and developing the disease. You have a 50% (1 in 2) chance of inheriting one abnormal gene. This would make you a carrier.