PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
development of a nasal spray that contains copies of the normal gene that is defective in person with cystic fibrosis
|
|
cutting DNA into fragments with restriction enzymes
|
|
modifying E. coli to produce indigo dye for coloring denim blue jeans
|
|
separation DNA fragments using gel electrophoresis
|
Detailed explanation-1: -Which of the following would be an example of gene therapy technology? Development of a nasal spray that contains copies of the normal gene that is defective in persons with cystic fibrosis. The human genome project has involved sequencing and mapping the human genome.
Detailed explanation-2: -Non-Integrating Gene Therapy DNA decides the “genetic message” in each cell, organ, and organism. with a correct copy of the CFTR gene is provided to an individual’s cells, but the DNA remains separate from the genome and is not permanent.
Detailed explanation-3: -Gene therapy is the use of a drug to treat disease by delivering therapeutic DNA into a patient’s cells. The most common form of gene therapy involves using DNA that encodes a functional, therapeutic gene to replace a mutated gene, e.g., treatment of SCID.