PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
Polygenic
|
|
Complete
|
|
Dominant
|
|
Autosomal
|
Detailed explanation-1: -“Polygenic inheritance is defined as quantitative inheritance, where multiple independent genes have an additive or similar effect on a single quantitative trait.” Polygenic inheritance is also known as multiple gene inheritance or multiple factor inheritance.
Detailed explanation-2: -Definition. A polygenic trait is a characteristic, such as height or skin color, that is influenced by two or more genes. Because multiple genes are involved, polygenic traits do not follow the patterns of Mendelian inheritance. Many polygenic traits are also influenced by the environment and are called multifactorial.
Detailed explanation-3: -Polygenic trait: also called quantitative or complex trait, a polygenic trait is determined by several genes and/or regulatory loci.
Detailed explanation-4: -Polygenic dominance is an interaction between alleles from a polygenic trait (a trait that involves multiple genes) where one allele dominates the other alleles. Eye color is an example of polygenic dominance where the brown (BB, Bb) allele dominates the alleles for blue (bb) and green (GG, Gg).
Detailed explanation-5: -Pleiotropy is a type of complex genetic inheritance in which one gene affects many different traits. The phenotype, or expressed trait, is determined by the genotype, which refers to an organism’s genetic makeup.