PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following would be true of all daughters born to a man with hemophilia, regardless of who the mother is? (3B3)
A
None of the daughters would have hemophilia nor would they carry the gene for hemophilia
B
All daughters would have hemophilia
C
All daughters would carry at least one gene for hemophilia but would not necessarily have the disorder
D
About 50% of the daughters would carry one gene for the disorder, and about 50% would have the disorder
Explanation: 

Detailed explanation-1: -However, all daughters of a man with hemophilia are considered obligate carriers of hemophilia because they must receive the affected X chromosome from their fathers to be female, and they can pass the gene to their sons.

Detailed explanation-2: -Which of the following would be true of all daughters born to a man with hemophilia, regardless of who the mother is?-All daughters would carry at least one gene for hemophilia but would not necessarily have the disorder.

Detailed explanation-3: -A man who has hemophilia and a woman who is a carrier have: a 25% (one in four) chance of having a son with hemophilia. a 25% chance of having a son with normal blood clotting. a 25% chance of having a daughter who is a carrier.

There is 1 question to complete.