PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Not the result of a genetic disorder.
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Both parents carry the recessive gene.
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CF is a chromosomal mutation and not related to parental genotypes.
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CF is caused by a mutation in pair 21.
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Detailed explanation-1: -The greatest risk factor for cystic fibrosis is a family history of the disease, especially if either parent is a known carrier. The gene that causes cystic fibrosis is recessive. This means that in order to have cystic fibrosis, children must inherit two copies of the gene, one from each parent.
Detailed explanation-2: -Cystic fibrosis is an example of a recessive disease. That means a person must have a mutation in both copies of the CFTR gene to have CF. If someone has a mutation in only one copy of the CFTR gene and the other copy is normal, he or she does not have CF and is a CF carrier.
Detailed explanation-3: -Cystic fibrosis (CF) is a genetic disease. This means that CF is inherited. A child will be born with CF only if two CF genes are inherited-one from the mother and one from the father. A person who has only one CF gene is healthy and said to be a “carrier” of the disease.