PATHOLOGY

Detailed explanation-1: -The most common type of chromosomal abnormality is known as aneuploidy, an abnormal chromosome number due to an extra or missing chromosome. Most people with aneuploidy have trisomy (three copies of a chromosome) instead of monosomy (single copy of a chromosome).

Detailed explanation-2: -Normally, meiosis causes each parent to give 23 chromosomes to a pregnancy. When a sperm fertilizes an egg, the union leads to a baby with 46 chromosomes. But if meiosis doesn’t happen normally, a baby may have an extra chromosome (trisomy), or have a missing chromosome (monosomy).

Detailed explanation-3: -Prader-Willi Syndrome (PWS): PWS is a genetic disorder involving a defect on chromosome 15. Down Syndrome: Williams Syndrome: Fragile X Syndrome: Smith-Magenis Syndrome: Angelman Syndrome: Smith-Lemli-Opitz Syndrome: Lesch-Nyhan Syndrome: More items