PATHOLOGY

Detailed explanation-1: -2. Less than 50% of the human genome codes for proteins.

Detailed explanation-2: -Therefore, at the layer of “genes, ‘’ 41.56% of the human genome is functional. However, only 1.15% of the genome represents protein-coding sequence (sum of all constitutive and alternative exons; 1.17% according to NCBI) and thus determines the functional genome at the layer of protein-coding nucleotides.

Detailed explanation-3: -But one of the great surprises of modern biology was definitely the discovery that the human genome encodes only  20, 000 protein-coding genes, representing less than 2% of the total genome se-quence (see Figure 1).