PATHOLOGY MCQ
GENETICS AND DISEASE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It can assess individual variability to many drugs.
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It can be used to determine the effectiveness of a drug.
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It provides important assessment data for gene therapy.
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It can assess the variability of drug responses due to single genes.
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Detailed explanation-1: -Pharmacogenomics is the study that deals with the relationship between genomic variations and their effect on drugs. Though the terms pharmacogenomics (PGx) and pharmacogenetics (PGt) are often used interchangeably, pharmacogenetics usually refers to the effect of a single gene on drug response.
Detailed explanation-2: -Pharmacogenetics may influence both the pharmacokinetics and pharmacodynamics of medications. This variability has relevance for dosing, therapeutic sensitivity, likelihood of side-effects, and risk for hypersensitivity reactions.
Detailed explanation-3: -Pharmacogenomics can improve your health by helping you know ahead of time whether a drug is likely to benefit you and be safe for you to take. Knowing this information can help your doctor find medicine that will work best for you.
Detailed explanation-4: -Pharmacogenomics is the study of how genes affect a person’s response to drugs. This field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications that can be prescribed based on a person’s genetic makeup.