PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is an example of ANEUPLOIDY? (3.2.2)
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Down syndrome
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sickle cell syndrome
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cystic fibrosis
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cancer
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Explanation:
Detailed explanation-1: -Down’s syndrome is an example of aneuploidy which is due to the trisomy of chromosome 21.
Detailed explanation-2: -Trisomy is the most common aneuploidy. In trisomy, there is an extra chromosome. A common trisomy is Down syndrome (trisomy 21).
Detailed explanation-3: -Down’s syndrome-Trisomy of 21st chromosome. Edward’s syndrome-Trisomy of 18th chromosome. Patau syndrome-Trisomy of 13th chromosome. Klinefelter’s syndrome-There is an additional number of the X chromosome, XXY. Turner’s Syndrome-One X chromosome is less, XO.
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