PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why does height in humans have such a wide variety of phenotypes?
A
It is controlled by multiple alleles.
B
It only has two alleles.
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Human features like height, eye color, and hair color come in lots of slightly different forms because they are controlled by many genes, each of which contributes some amount to the overall phenotype.

Detailed explanation-2: -Answer and Explanation: Traits that show a wide range of phenotypes, such as human height and skin color, are due to the cumulative expression of alleles of many genes and interactions with the environment.

Detailed explanation-3: -A polygenic trait is a characteristic, such as height or skin color, that is influenced by two or more genes. Because multiple genes are involved, polygenic traits do not follow the patterns of Mendelian inheritance. Many polygenic traits are also influenced by the environment and are called multifactorial.

Detailed explanation-4: -Because height is determined by multiple gene variants (an inheritance pattern called polygenic inheritance), it is difficult to accurately predict how tall a child will be.

Detailed explanation-5: -Height and other similar features are controlled not just by one gene, but rather, by multiple (often many) genes that each make a small contribution to the overall outcome. This inheritance pattern is called polygenic inheritance (poly– = many).

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