PATHOLOGY

PATHOLOGY MCQ

HAEMOPOIETIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A 67-year-old female presented with painless enlargement of lymph nodes. Histological examination of a biopsy sample revealed that the whole lymph node pattern was unclear, with heterogeneous cellular infiltrate. It included abnormal, immature cells admixed with lymphocytes, eosinophils, plasma cells and macrophages. Binucleated Berezovsky-Reed-Sternberg cells, where surrounded by multiple cell types. What is the most likely diagnosis?
A
Acute myeloleukemia
B
Chronic myeloleukemia
C
Lymphogranulomatosis
D
Mycosis fungoides
E
Tuberculosis
Explanation: 

Detailed explanation-1: -The most common symptom of Hodgkin lymphoma is a painless swelling in a lymph node, usually in the neck, armpit or groin.

Detailed explanation-2: -Non-Hodgkin lymphoma can cause lymph nodes to become enlarged. Enlarged lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin or underarm areas, or above the collar bone), may be seen or felt as lumps under the skin. These are usually not painful.

Detailed explanation-3: -Generalized lymphadenopathy is most often associated with systemic viral infections. Infectious mononucleosis results in widespread adenopathy. Roseola infantum (caused by human herpes virus 6), cytomegalovirus (CMV), varicella, and adenovirus all cause generalized lymphadenopathy.

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