PATHOLOGY

Detailed explanation-1: -Thromboembolic events and cardiovascular disease are the most prevalent complications in patients with polycythemia vera (PV) compared with other myeloproliferative disorders and are the major cause of morbidity and mortality in this population.

Detailed explanation-2: -Myeloproliferative neoplasms (MPNs) such as polycythemia Vera (PV) and Essential Thrombocythemia (ET) can be associated with a high risk of both venous and arterial thrombosis.

Detailed explanation-3: -Blood clots The most urgent risk from polycythemia vera is the tendency for blood clotting. A blood clot that travels to your heart or brain can cause a heart attack or stroke. A clot that gets stuck in your lungs (pulmonary embolism) can cause pulmonary hypertension, leading to heart failure.

Detailed explanation-4: -It causes your bone marrow to make too many red blood cells. These excess cells thicken your blood, slowing its flow, which may cause serious problems, such as blood clots.