PATHOLOGY

Detailed explanation-1: -During Phase 2, a type of white blood cells called neutrophils enter the wound to destroy bacteria and remove debris.

Detailed explanation-2: -Inflammatory Phase The fluid engorgement allows healing and repair cells to move to the site of the wound. During the inflammatory phase, damaged cells, pathogens, and bacteria are removed from the wound area.

Detailed explanation-3: -The second phase of wound healing is called the Inflammatory Phase. It involves phagocytic cells that release reactive oxygen species, lasting for up to seven days in acute wounds and longer in chronic wounds.

Detailed explanation-4: -Wound healing is classically divided into 4 stages: (A) hemostasis, (B) inflammation, (C) proliferation, and (D) remodeling. Each stage is characterized by key molecular and cellular events and is coordinated by a host of secreted factors that are recognized and released by the cells of the wounding response.

Detailed explanation-5: -Analogous to pro-inflammatory macrophages, M1 macrophages dominate during the pro-inflammatory phase of wound healing, and through their highly phagocytic behavior, serve the role of sanitizing the wound and clearing it of dead tissue.