PATHOLOGY

Detailed explanation-1: -Remodelling is the final phase of the healing process in which the granulation tissue matures into scar and tissue tensile strength is increased (Figure 23.5).

Detailed explanation-2: -After scar tissue forms in the body, it is not permanent. The scar tissue can become stronger and better able to tolerate stretching forces through a process called remodeling. Remodeling scar tissue is a must to ensure that the muscle, tendon, skin, bone, or ligament becomes normal, healthy tissue again.

Detailed explanation-3: -The third phase of healing consists of remodeling, which begins two to three weeks after the onset of the lesion and can last for one year or more. The core aim of the remodeling stage is to achieve the maximum tensile strength through reorganization, degradation, and resynthesis of the extracellular matrix.

Detailed explanation-4: -Scar Remodeling This process starts around 3 weeks after injury and peaks around 3-6 months, and can cause a scar that was initially subtle to appear darker, thicker, and shortened. Eventually, as reorganization is completed, the scar tissue softens and fades in color as the excess blood vessels in the scar disappear.

Detailed explanation-5: -Remodeling phase – This phase can continue for six months to one year after injury. Collagen continues to increase and the tissue begins to contract with the help of fibroblasts, both of which add strength to the new tissue. Excessive collagen can cause scar tissue formation.