PATHOLOGY

Detailed explanation-1: -Inflammation. Inflammation, the next stage of wound healing occurs within the first 24 hours after injury and can last for up to 2 weeks in normal wounds and significantly longer in chronic non-healing wounds (Figure 23.3).

Detailed explanation-2: -The second phase of wound healing is called the Inflammatory Phase. It involves phagocytic cells that release reactive oxygen species, lasting for up to seven days in acute wounds and longer in chronic wounds.

Detailed explanation-3: -Phase 4: Maturation Phase During the Maturation phase, the new tissue slowly gains strength and flexibility. Here, collagen fibers reorganize, the tissue remodels and matures and there is an overall increase in tensile strength (though maximum strength is limited to 80% of the pre-injured strength).

Detailed explanation-4: -Swelling. Swelling is a sign that your immune system is repairing your wound. The blood vessels widen to ease blood flow and send oxygen, vitamins, and minerals to your injury. This stage shouldn’t last longer than five days.

Detailed explanation-5: -The inflammatory response following tissue injury plays important roles both in normal and pathological healing. Immediately after injury, the innate immune system is activated, setting in motion a local inflammatory response that includes the recruitment of inflammatory cells from the circulation.