PATHOLOGY

Detailed explanation-1: -All patients with a suspected myocardial infarction should be given aspirin. It is a powerful antiplatelet drug, with a rapid effect, which reduces mortality by 20%. Aspirin, 150-300 mg, should be swallowed as early as possible.

Detailed explanation-2: -Treatment / Management [17][18] Patients should undergo percutaneous coronary intervention (PCI) within 90 minutes of presentation at a PCI capable hospital or within 120 minutes if transfer to a PCI capable hospital is required.

Detailed explanation-3: -After about 3 to 6 hours, though, the zone of necrosis extends through the entire wall thickness, called a transmural infarct, which this time shows up as ST-segment elevation on ECG, which is why they’re sometimes called STEMIs, or ST elevation myocardial infarctions.

Detailed explanation-4: -Days 1-3 are marked by “acute inflammation”, in which neutrophils infiltrate the ischemic tissue. A major complication during this period is fibrinous pericarditis, particularly in transmural ventricular wall damage (an infarct that impacted all 3 layers of the heart, the epicardium, myocardium, and endocardium).