PATHOLOGY

Detailed explanation-1: -Remodelling. Remodelling is the final phase of the healing process in which the granulation tissue matures into scar and tissue tensile strength is increased (Figure 23.5).

Detailed explanation-2: -The third phase of healing consists of remodeling, which begins two to three weeks after the onset of the lesion and can last for one year or more. The core aim of the remodeling stage is to achieve the maximum tensile strength through reorganization, degradation, and resynthesis of the extracellular matrix.

Detailed explanation-3: -Scar tissue formation characterizes the final Remodeling Phase (also known as Maturation). It may occur over months or years, depending on the initial severity of the wound, its location, and treatment methods. During this phase, the new tissue gradually becomes stronger and more flexible.

Detailed explanation-4: -The first phase of scar tissue formation is the inflammatory phase. This phase occurs immediately after trauma. Blood clotting begins almost instantly and is followed by migration of macrophages and histiocytes to start débriding the area.

Detailed explanation-5: -Scars form as part of the healing process after your skin has been cut or damaged. The skin repairs itself by growing new tissue to pull together the wound and fill in any gaps caused by the injury. Scar tissue is made primarily of a protein called collagen. Scars develop in all shapes and sizes.