PATHOLOGY

Detailed explanation-1: -The primary characteristic during this stage is inflammation. One of the clinical characteristics is the presence of pain in the early part of the range of motion. In some patients, even the slightest movement may produce pain.

Detailed explanation-2: -Acute phase reactants (APR) are inflammation markers that exhibit significant changes in serum concentration during inflammation. These are also important mediators produced in the liver during acute and chronic inflammatory states.

Detailed explanation-3: -Acute-phase proteins (APPs) are a class of proteins whose concentrations in blood plasma either increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute-phase response).