PATHOLOGY

Detailed explanation-1: -Proliferation phase As the inflammation subsides, proliferation becomes a major theme with the focus on covering the wound surface (i.e., re-epithelialization), restoring the vascular network and forming granulation tissue.

Detailed explanation-2: -The proliferative phase is characterized by the formation of granulation tissue, reepithelialization, and neovascularization. This phase can last several weeks.

Detailed explanation-3: -The primary aim of the proliferation phase is to fill the wound defect. Fibroblasts migrate to the wound site and synthesize collagen and elastin fibers which form the extracellular matrix necessary for granulation tissue formation.

Detailed explanation-4: -In the proliferation stage, your body creates scar tissue to repair your injury. This phase of healing starts within 24 – 48 hours, peaks at around 2 – 3 weeks after your injury and stops after around 4 – 6 months. This is the reason why you will still be experiencing symptoms a couple of weeks after your injury.