PATHOLOGY

Detailed explanation-1: -Antibiotics may also be used if the ulcer becomes infected, but they don’t help ulcers to heal. However, unless the underlying cause of the ulcer is addressed, there’s a high risk of a venous leg ulcer recurring after treatment. Underlying causes could include immobility, obesity, previous DVT, or varicose veins.

Detailed explanation-2: -Causes Venous leg ulcer A venous leg ulcer can develop after a minor injury if there’s a problem with the circulation of blood in your leg veins. This happens when the pressure inside the veins increases. This constant high pressure can gradually damage the tiny blood vessels in your skin and make it fragile.

Detailed explanation-3: -Research has shown that leg ulcers are colonized by both Gram-positive and Gram-negative bacteria. The most common Gram-negative microorganisms isolated in leg ulcer infections are Pseudomonas aeruginosa and Escherichia coli, while Staphylococcus aureus predominates among the Gram-positive microorganisms.

Detailed explanation-4: -A leg ulcer is a long-lasting (chronic) sore that takes more than 2 weeks to heal. It usually develops on the inside of the leg, between the knee and the ankle. The symptoms of a venous leg ulcer include pain, itching and swelling in the affected leg.