PATHOLOGY

Detailed explanation-1: -The released chemical mediators include (1) vasoactive amines such as histamine and serotonin, (2) peptide (e.g., bradykinin), and (3) eicosanoids (e.g., thromboxanes, leukotrienes, and prostaglandins).

Detailed explanation-2: -For example, cytokines can tell an immature cell to mature into a white blood cell capable of fighting infection. Cell proliferation: Cytokines can tell a cell to make more cells just like it. For example, cytokines can tell a white blood cell to make more white blood cells to fight infection.

Detailed explanation-3: -One of the best-known chemical mediators released from cells during inflammation is histamine, which triggers vasodilation and increases vascular permeability. Stored in granules of circulating basophils and mast cells, histamine is released immediately when these cells are injured.

Detailed explanation-4: -Cytokines are the mediators of the immune system. They are small proteins of around 25 kD that are produced in response to a stimulus (ie, invading microbes) by numerous cell types.