PATHOLOGY

Detailed explanation-1: -Immune cells may also activate resulting to fever. At the end of the inflammatory phase, monocyte cells clean up dead tissue cells and foreign matter in the injury site.

Detailed explanation-2: -Haemostasis Phase. At the time of injury, the fibrin clot forms the provisional wound matrix and platelets release multiple growth factors initiating the repair process.

Detailed explanation-3: -Initially fibrin(ogen) acts as a provisional matrix supporting incoming leukocytes and acting as reservoir for growth factors. It later goes on to support re-epithelialization, angiogenesis, and fibroplasia. Importantly, removal of fibrin(ogen) from the wound is essential for wound healing to progress.

Detailed explanation-4: -Among amino-acids, those that play an important role in wound healing, are arginine and glutamine. The first is a precursor of nitric oxide and proline, which in turn are essential for the inflammatory process [34] and synthesis of collagen [35, 36].