PATHOLOGY

Detailed explanation-1: -Inflammation plays an important role in tissue repair and regeneration. Recent work reveals that inflammatory signaling increases DNA accessibility so as to promote phenotypic fluidity in response to injury.

Detailed explanation-2: -The wound healing process is usually characterized as four sequential but overlapping phases: haemostasis (0–several hours after injury), inflammation (1–3 days), proliferation (4–21 days) and remodelling (21 days–1 year) [1].

Detailed explanation-3: -Inflammation underlies many chronic and degenerative diseases, but it also mitigates infections, clears damaged cells and initiates tissue repair.

Detailed explanation-4: -Oxygenation. Infection. Foreign body. Venous sufficiency.