PATHOLOGY

Detailed explanation-1: -Dendritic cells are able to induce an initial immune response in inactive or resting T lymphocytes. To do this, the dendritic cells capture antigens from invading bodies, which they process and then present on their cell surface, along with the necessary accessory or co-stimulation molecules.

Detailed explanation-2: -T cells use structures on their surface, aptly called T cell receptors (TCRs) to very specifically recognize abnormal or unfamiliar molecules called antigens, which might be present on invading or unhealthy target cells. Each T cell receptor recognizes one particular antigen.

Detailed explanation-3: -T and B cells are activated when they recognize small components of antigens, called epitopes, presented by APCs, illustrated in Figure 2. Figure 2. An antigen is a macromolecule that reacts with components of the immune system. A given antigen may contain several motifs that are recognized by immune cells.

Detailed explanation-4: -CD8+ T cells When a CD8+ T Cell develops its effector functions, it is converted into a cytotoxic T Cell able to attack cells directly and destroy those that are malignant or infected with virus (39).