PATHOLOGY MCQ
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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How does the thymus change in size as we age?
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increases exponentially
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decreases exponentially
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It is not effected
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initially increases until adolescent and then decreases through old age
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Explanation:
Detailed explanation-1: -Galen was the first who noted that the thymus diminishes as the organism ages. [6] The thymus grows from birth to 2–3 years of age, then it reaches its maximum weight (30–40 gr), and then begins to shrink in the period of adolescence because of the influence of sex hormones present in the bloodstream.
Detailed explanation-2: -Thymic involution is the genetically programmed aging process via which the thymus undergoes a progressive reduction in size due to the loss of thymic epithelial cells and decrease in thymopoiesis (Bar-Dayan, Afek, Bar-Dayan, Goldberg, & Kopolovic, 1999; Taub & Longo, 2005).
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