PATHOLOGY MCQ
IMMUNE RESPONSE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It divides by mitosis producing a clone of cells.
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It begins transcription and produces antigens.
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It differentiates into memory cells.
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It produces antibodies using its extensive rough endoplasmic reticulum (rER).
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Detailed explanation-1: -B lymphocyte activation is initiated by the binding of antigens to the clonally expressed B cell receptors (BCRs) triggering signaling cascades that lead to the transcription of a variety of genes associated with B cell activation.
Detailed explanation-2: -B cells are first activated to divide via interactions between the MCRs and their complementary antigens.
Detailed explanation-3: -Different B cells have different shaped antibodies on their surface, so only the B cells with the correct-shaped antibodies will be activated. Once they are activated, the B cells divide by mitosis and differentiate into two kinds of cell-plasma cells and memory cells.
Detailed explanation-4: -Interaction with antigens causes B cells to multiply into clones of immunoglobulin-secreting cells. Then the B cells are stimulated by various cytokines to develop into the antibody-producing cells called plasma cells.