PATHOLOGY

Detailed explanation-1: -Immunoglobulin D (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes where it is usually co-expressed with another cell surface antibody called IgM.

Detailed explanation-2: -Expression of the membrane-bound form of the immunoglobulin (Ig) as part of the antigen receptor is indispensable for both the development and the effector function of B cells. Among five known isotypes, IgM and IgD are the common B cell antigen receptors (BCRs) that are co-expressed in naïve B cells.

Detailed explanation-3: -IgA, IgD, IgE, IgM and IgG are those variants. They specifically bind to antigens and create an immune response. The immunoglobulins are nothing but antibodies that get attached to the B-Cell receptors.

Detailed explanation-4: -IgD (IgD) is a monomeric antibody isotype that is expressed in the plasma membranes of immature B-lymphocytes. IgD is also produced in a secreted form that is found in small amounts in blood serum. Secreted IgD is made up of two heavy chains of the delta class, and two light chains.