PATHOLOGY

Detailed explanation-1: -Edema is a swelling from liquid accumulation in body tissues. Injuries in tissues or organs may cause this disorder leading to chemical mediators releasing and triggering the inflammatory process. Inflammatory mediators, when released in response to injuries, promote biological reactions at the affected site.

Detailed explanation-2: -At the tissue level, inflammation is characterized by redness, swelling, heat, pain, and loss of tissue function, which result from local immune, vascular and inflammatory cell responses to infection or injury [5].

Detailed explanation-3: -inflammation, a response triggered by damage to living tissues. The inflammatory response is a defense mechanism that evolved in higher organisms to protect them from infection and injury.

Detailed explanation-4: -Included among these mediators are arachidonic acid derivatives (leukotrienes and prostaglandins), vasoactive peptides (kinins), phospholipid mediators (platelet activating factor), and cytokines (interleukins and other bioresponse modifiers).