PATHOLOGY MCQ
INFLAMMATION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Phagocytes drop to the outer edge of a blood vessels
|
|
|
Phagocytes roll along the outer edge of the blood vessel
|
|
|
Phagocytes attach to the outer edge of the blood vessel
|
|
|
Phagocytes move through the outer edge of the blood vessel
|
Detailed explanation-1: -In margination, leukocytes assume marginal positions in the blood vessels. They intermittently stick to the walls of the venules and roll along them until they become firmly attached to the vessel wall (adhesion). At this point, they begin to move out of the vessel.
Detailed explanation-2: -In physiology, margination refers to the migration of white blood cells (WBCs) toward the endothelium during blood flow and is relevant to the process of inflammation.
Detailed explanation-3: -Phagocytosis is the primary method used by the body to remove free microorganisms in the blood and tissue fluids. An inflammatory response to injury and/or infection allows phagocytes to leave the bloodstream, enter the tissue, and go to the site of infection or injury.
Detailed explanation-4: -To reach the site of infection, phagocytes leave the bloodstream and enter the affected tissues. Signals from the infection cause the endothelial cells that line the blood vessels to make a protein called selectin, which neutrophils stick to when they pass by.