PATHOLOGY

Detailed explanation-1: -Impaired healing in diabetes is the result of a complex pathophysiology involving vascular, neuropathic, immune, and biochemical components [3]. Hyperglycemia correlates with stiffer blood vessels which cause slower circulation and microvascular dysfunction, causing reduced tissue oxygenation [2].

Detailed explanation-2: -Slow healing wounds can be a symptom of undiagnosed diabetes, particularly if other symptoms are also present. Slow healing of wounds, including cuts, grazes and blisters, can be particularly problematic if they affect the feet of someone with diabetes and if not treated properly, can raise the risk of amputation.