PATHOLOGY

Detailed explanation-1: -Granulomatous appendicitis is a rare condition that may be discovered incidentally in a patient with a clinical presentation of acute appendicitis. Occurring in about 0.1% to 2.0% of all appendectomy specimens. Various infectious agents (Yersinia spp., Mycobacterium tuberculosis, and Schistosoma spp.)

Detailed explanation-2: -Granulomatous inflammation of muscle is usually associated with sarcoidosis but can also be seen in infectious disease, inflammatory bowel disease, foreign body reactions, thymoma, lymphoma, and myasthenia gravis. It may also occur without any evidence of systemic disease.

Detailed explanation-3: -Appendicitis is the inflammation of the vermiform appendix. It typically presents acutely, within 24 hours of onset, but can also present as a more chronic condition. Classically, appendicitis initially presents with generalized or periumbilical abdominal pain that later localizes to the right lower quadrant.

Detailed explanation-4: -Granulomatous appendicitis is an uncommon subtype of appendicitis and can be caused by a variety of conditions including systemic disorders such as Crohn’s disease and sarcoidosis, as well as infections such as Mycobacterium tuberculosis, Yersinia pseudotuberculosis, parasites, and fungi [2].