PATHOLOGY

PATHOLOGY MCQ

INFLAMMATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Role of macrophages in chronic inflammation
A
Degranulates and release histamine
B
Produce growth factor ( GF ) for tissue repair
C
Secrete cytokines and eicosanoids
D
Display antigens to T lymphocytes and respond to signals from T cells
Explanation: 

Detailed explanation-1: -Professional antigen-presenting cells, including macrophages, B cells and dendritic cells, present foreign antigens to helper T cells, while virus-infected cells (or cancer cells) can present antigens originating inside the cell to cytotoxic T cells.

Detailed explanation-2: -Macrophage as an inducer of the inflammation Resting macrophages produce only low levels of pro-inflammatory mediators. When an inflammatory process occurs, tissue-resident and recruited macrophages proliferate, differentiate, or become activated under the effect of interleukins or growth factors.

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