PATHOLOGY MCQ
INFLAMMATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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pain
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fever
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smooth muscle contraction
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dilation of arterioles
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Detailed explanation-1: -Inflammatory mediators are molecules produced by activated cells that intensify and prolong the inflammatory response. Histamine is a potent inflammatory mediator, commonly associated with allergic reactions, promoting vascular and tissue changes and possessing high chemoattractant activity.
Detailed explanation-2: -Mast cells, platelets, and basophils produce the vasoactive amines serotonin and histamine. Histamine causes arteriolar dilation, increased capillary permeability, contraction of nonvascular smooth muscle, and eosinophil chemotaxis and can stimulate nociceptors responsible for the pain response.
Detailed explanation-3: -Chemical mediators that promote vasodilation include: histamine, prostaglandins, and nitric oxide.