PATHOLOGY

Detailed explanation-1: -Anything that raises capillary pressures, reduces oncotic pressure, increases endothelial permeability, or impairs lymphatic drainage will result in edema.

Detailed explanation-2: -Cells and fluids This decreases the oncotic pressure gradient and so the hydrostatic pressure in the capillaries forces out more water, increasing the production of the tissue fluid. This enhanced rate of tissue fluid formation results in the tissue swelling referred to as oedema.

Detailed explanation-3: -Edema results from increased movement of fluid from the intravascular to the interstitial space or decreased movement of water from the interstitium into the capillaries or lymphatic vessels. The mechanism involves one or more of the following: Increased capillary hydrostatic pressure. Decreased plasma oncotic pressure.

Detailed explanation-4: -In many diseases, including cancer and chronic inflammatory conditions, the vascular barrier disintegrates and leakage increases and may become chronic. The leakage of larger molecules and cells results in edema, inflammation, and often disease progression.

Detailed explanation-5: -Edema is a swelling from liquid accumulation in body tissues. Injuries in tissues or organs may cause this disorder leading to chemical mediators releasing and triggering the inflammatory process. Inflammatory mediators, when released in response to injuries, promote biological reactions at the affected site.