PATHOLOGY

Detailed explanation-1: -So, even though we will continue to call it “liver regeneration, ‘’ the more accurate term for what happens in the liver is compensatory hyperplasia [3]. Although this term may sound complicated, it actually means an increase in the size of the liver caused by an increase in the number of cells.

Detailed explanation-2: -The liver has a unique capacity among organs to regenerate itself after damage. A liver can regrow to a normal size even after up to 90% of it has been removed. But the liver isn’t invincible. Many diseases and exposures can harm it beyond the point of repair.

Detailed explanation-3: -Human liver is able to regenerate thanks to a hyperplastic reaction in the remnant liver[1]. However, if after resection, the remnant liver is less than 20% of the original liver volume, liver function might not sustain metabolic, synthetic, and detoxifying needs, leading to post-resection liver failure[2].