PATHOLOGY MCQ
INFLAMMATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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TLR
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IL-1R
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IL-6R
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All of the above activate the primary pro-inflammatory pathway
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Detailed explanation-1: -Mast cells, which reside in connective tissue matrices and on epithelial surfaces, are effector cells that initiate inflammatory responses.
Detailed explanation-2: -Therefore antibodies are not a part of inflammatory response as they are involved in humoral immunity.
Detailed explanation-3: -Infection of cells by microorganisms activates the inflammatory response. The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors.
Detailed explanation-4: -The goals of the inflammatory response are to: Prevent initial establishment of infection or remove damaged tissue. Prevent the spread of infection or repair damaged tissue. Recruit effector cells if the immune cells of the innate immune system cannot control infection or repair damaged tissue.