PATHOLOGY

Detailed explanation-1: -Larger diameter axons have a higher conduction velocity, which means they are able to send signals faster.

Detailed explanation-2: -The speed of nerve conduction does not depend on the diameter of axon only rather it depends on the diameter of the nerve fibre. The diameter of nerve fibre is axon, neurilemma, and myelin sheath in myelinated axons while axon and neurilemma in unmyelinated fibre.

Detailed explanation-3: -Axon diameter is important since ions must move through the cytoplasm to depolarize surrounding areas of the plasma membrane. Cytoplasm offers lower resistance to ion movement than the axon membrane. An axon with a larger diameter has less resistance.

Detailed explanation-4: -In summary, increasing axon diameters accelerated action potential conduction along the axons. This finding is in line with cable theory (Goldstein and Rall, 1974) as axons of increased diameter have less internal electrical resistance, which facilitates the spread of action potential.