PATHOLOGY

Detailed explanation-1: -Common sites of localized amyloidosis are skin, larynx, and bladder. Localized form rarely progress to systemic forms, however, are notorious to have local recurrence. Systemic amyloidosis is characterized by deposition of amyloid at multiple sites and visceral organ leading to organ dysfunction.

Detailed explanation-2: -AA-amyloidosis is the most common form of amyloidosis in domestic animals. It is associated with chronic inflammatory or neoplastic diseases (nonimmunocyte dyscrasia), or it may be idiopathic, where no underlying disease is found [16, 17].