PATHOLOGY MCQ
URINARY SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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At which of these sites is the osmotic pressure lowest? (least concentrated filtrate)
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glomerular capillary
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proximal tubule
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bottom of the loop of Henle
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first part of the distal tubule
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collecting duct
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Explanation:
Detailed explanation-1: -The filtrate then enters the thick ascending limb, which is permeable to sodium ions. The sodium ions rush out of the filtrate into the interstitium, which now has lower concentration than the filtrate.
Detailed explanation-2: -The thick ascending limb is nearly impermeable to water and no aquaporin proteins have been detected in this nephron segment (reviewed in [1]). The thick ascendling limb has a low NaCl permeability, but it vigorously transports NaCl from the tubular lumen to the medullary interstitium by an active transport mechanism.
There is 1 question to complete.