PATHOLOGY

Detailed explanation-1: -Chronic kidney disease, also called chronic kidney failure, involves a gradual loss of kidney function. Your kidneys filter wastes and excess fluids from your blood, which are then removed in your urine.

Detailed explanation-2: -In chronic kidney disease, ongoing failure of individual nephrons leads to the progressive loss of renal function. This process results in part from a cellular and molecular response to injury that represents an attempt to maintain homeostasis but instead initiates a program that damages the nephron.

Detailed explanation-3: -Chronic kidney disease (CKD) is a progressive and irreversible deterioration of renal function. That means the kidneys slowly lose their ability to eliminate toxins and control the amount of water in the body.