PATHOLOGY MCQ
URINARY SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Glucose
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Urea
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Medication
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Drugs
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Ammonia
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Detailed explanation-1: -The PCT secretes: Organic acids and bases – e.g. bile salts, oxalate and catecholamines (waste products of metabolism) Hydrogen ions (H+) – important in maintaining acid/base balance in the body. H+ secretion allows reabsorption of bicarbonate via the use of the enzyme carbonic anhydrase (Fig 2).
Detailed explanation-2: -Minor components of basolateral NH4+ uptake via Na+-K+-ATPase and by basolateral K+ channels are not shown. Figure modified from reference (180) with permission. The proximal tubule also can reabsorb luminal ammonia; this appears to occur primarily in the late proximal tubule (56).
Detailed explanation-3: -Tubular secretion can be either active or passive or co-transport. Substances mainly secreted into renal tubule are; H+, K+, NH3, urea, Creatinine, histamine and drugs like penicillin.