IMMUNOLOGY

Detailed explanation-1: -Immunogenicity is the ability to induce a humoral and/or cell-mediated immune response. Antigenicity is the ability to specifically combine with the final products of the immune response (i.e., secreted antibodies and/or surface receptors on T cells) (Owen et al.

Detailed explanation-2: -Humoral immunity is also called antibody-mediated immunity. With assistance from helper T cells, B cells will differentiate into plasma B cells that can produce antibodies against a specific antigen. The humoral immune system deals with antigens from pathogens that are freely circulating, or outside the infected cells.

Detailed explanation-3: -Immunogenicity is defined as the ability of cells/tissues to provoke an immune response and is generally considered to be an undesirable physiological response.

Detailed explanation-4: -TH2 cells initiate the humoral immune response by activating naive antigen-specific B cells to produce IgM antibodies. These TH2 cells can subsequently stimulate the production of different isotypes, including IgA and IgE, as well as neutralizing and/or weakly opsonizing subtypes of IgG.