IMMUNOGLOBULINS
MONOCLONAL ANTIBODIES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Taken from bone marrow
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From a clone of a single cell
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From an embryo
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All of the above
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Detailed explanation-1: -A monoclonal antibody is an antibody that is the product of a single B cell clone. Production of monoclonal antibodies involves the in vitro combination of two types of cells. The first type of cell is a B cell that produces a single, unique antibody.
Detailed explanation-2: -Traditionally, monoclonal antibodies are generated via stable clones of immortalized B-cells either by injecting and collecting ascites from a mouse or culturing the antibody expressing B-cells and collecting the supernatant.
Detailed explanation-3: -A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.