IMMUNOLOGY

ANTIGENS

ANTIGENS AND IMMUNOGENICITY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Antigen, when injected in the body activates its specific lymphocytes in the
A
blood circulation
B
draining lymph nodes
C
MALT (mucosa associated
D
spleen lymphoid tissue
Explanation: 

Detailed explanation-1: -The response to the antigen by the lymphocytes is made in peripheral lymphoid organs. The filtration of the pathogen blood occurs in spleen, along with the cognition of lymphocytes. Therefore, option (C) is correct.

Detailed explanation-2: -Majority of the lymphocytes enter the lymph nodes via specialised vessels called high endothelial venules (HEV). The remaining lymphocytes (15–20%), together with dendritic cells and antigens, enter the lymph nodes via afferent lymphatics. Lymphocytes leave the lymph nodes via efferent lymphatics.

Detailed explanation-3: -A type of molecule found on the surface of most cells in the body. Human lymphocyte antigens play an important part in the body’s immune response to foreign substances. They make up a person’s tissue type, which varies from person to person.

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